Minireview: Endocrine Disruptors: Past Lessons and Future Directions
نویسندگان
چکیده
منابع مشابه
Minireview: Endocrine Disruptors: Past Lessons and Future Directions.
Within the past few decades, the concept of endocrine-disrupting chemicals (EDCs) has risen from a position of total obscurity to become a focus of dialogue, debate, and concern among scientists, physicians, regulators, and the public. The emergence and development of this field of study has not always followed a smooth path, and researchers continue to wrestle with questions about the low-dose...
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Spirochaetes today are often sidelined as an interesting exception within the microbial world, yet spirochaetes have played a major role in our understanding of microbial pathogenesis. As a group, they have challenged our established understanding of microbial infections, and still have a plethora of other secrets to disclose. Within this themed issue, we examine a range of spirochaetal example...
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BACKGROUND My research program in the 1970–1990 period was primarily focused on the chemistry, toxicology and mechanisms of action of highly persistent organochlorine environmental contaminants including the polychlorinated biphenyls (PCBs), dibenzofurans and dibenzop-dioxins (Figure 1). Since environmental samples and human residues of these organohalogen compounds (OCs) (or persistent organic...
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Law and science combine in the estimation of risks from endocrine disruptors (EDs) and actions for their regulation. For both, dose–response models are the causal link between exposure and probability (or percentage change) of adverse response. The evidence that leads to either regulations or judicial decrees is affected by uncertainty and limited knowledge, raising difficult policy issues that...
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ژورنال
عنوان ژورنال: Molecular Endocrinology
سال: 2016
ISSN: 0888-8809,1944-9917
DOI: 10.1210/me.2016-1096